Scientists Were Wrong for Decades: What Looked Like DNA Knots Turned Out To Be Something Far More Twisted

What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing an overlooked mechanism with major implications. For decades, researchers interpreted complex electrical patterns seen when DNA moved through nanopores as signs that the molecule was forming knots. Nanopore experiments, which are widely used to study genetic material, [...]