Deciphering symbiotic code: Research unlocks 'secret handshake' between legumes and rhizobia

In a study published in Science, researchers have resolved, for the first time, the high-resolution crystal structure of the complex formed between the NodD protein of pea rhizobia and a flavonoid compound (hesperetin). They elucidate how NodD recognizes flavonoids and reveal key structural elements in NodD that determine the specificity of signal recognition.